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Improving the diagnosis
of tuberculosis
in children

More info
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The Decide-TB project is an implementation research project aiming to improve the diagnosis and management of tuberculosis in children by using treatment decision algorithms (TDAs).

These algorithms will help clinicians to make rapid and consistent decisions for the treatment of tuberculosis in children.

About the project

The Decide-TB project will

  • Use treatment decision algorithms (TDAs) in district hospitals and primary health centres
  • Evaluate how TDAs increase the number of children started on TB treatment and if they detect TB accurately
  • Develop tools, procedures, and training curricula for use of TDAs by healthcare workers
  • Support the integration of TDAs into practices and policy

The project will be implemented from 2023 to 2027 in Mozambique and Zambia, 2 countries with high TB-burden in sub-Saharan Africa.

Decide-TB is funded by the European Union.

Key figures

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1 090 000

new tuberculosis cases
in children in 2022

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400 000

TB cases in children were
notified to WHO in 2022

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226 000

children died because
of tuberculosis in 2022

Latest news

Decide TB is delivering its first presentations on Tuesday, 18 November at the Union Conference 2025 in Copenhagen (18–21 November).

DecideTB Newsletter 5 March 2026 final
24Mar2026

Our Decide TB Newsletter 5 is online — on World TB Day!

As we commemorate World TB Day this March 24, please find our Newsletter 5 As With Treatment Decision Algorithms (TDAs) now implemented in all participating facilities in the 10 districts in Mozambique and Zambia, the project reaches a pivotal moment. The project focus now turns to data consolidation, analysis, and translation of findings into evidence […]

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DecideTB PLOS Medicine Visual
18Nov2025

Decide TB Publication in PLOS Medicine

Retrospective individual participant data analysis assesses diagnostic accuracy of WHO algorithms for childhood tuberculosis In 2023, 10.8 million people fell ill with tuberculosis (TB) and 1.25 million died, confirming TB as the world’s leading infectious disease killer. Among them, an estimated 1.2 million were children, yet less than half received proper diagnosis and treatment. To […]

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DecideTB Newsletter 4 November 2025 def
03Nov2025

Decide TB Newsletter n°4 – November 2025

Two years and a half after its launch, the Decide TB project has reached an important milestone: health facilities in all study districts of Zambia and Mozambique have now transitioned from the standard of care to implementing treatment decision algorithms (TDAs) for childhood TB diagnosis. On this occasion, we are pleased to share the Decide […]

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DecideTB Post CM Film
01Sep2025

Decide TB Community Engagement: A Live Example from Luanshya

Community mobilization is essential in the fight against tuberculosis, helping to raise awareness, reduce stigma, and encourage people to seek timely care. As part of its efforts to improve TB awareness and access to care, Decide TB conducted community mobilization activities in Luanshya District, Zambia, in May 2025. The activities brought together a wide range […]

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